There is currently a problem in Physics; How to combine Classical Physics with Quantum Physics, into a Grand Unified Theory of Everything.
In my opinion, Hawkings, being the brightest physicist, thinks that there will not be a Theory of Everything.
Stephen Hawking says there’s no theory of everything
https://www.newscientist.com/blogs/culturelab/2010/09/stephen-hawking-says-theres-no-theory-of-everything.html
How do you square deterministic Classical Physics with the probabilistic Quantum Physics?
I think, the reason physicists cannot find the theory is because they ignore one thing in the universe as part of physics. Life.
This was not always so, Erwin Schrödinger wrote a book “What is Life?” that touched on DNA among other ideas. This became a taboo, but thankfully it is starting to come up again.
For instance:
Quantum biology
https://en.wikipedia.org/wiki/Quantum_biology
Quantum Tunnelling to the Origin and Evolution of Life
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768233/
Quantum Criticality at the Origin of Life
http://arxiv.org/abs/1502.06880
Quantum cognition
https://en.wikipedia.org/wiki/Quantum_cognition
You’re not irrational, you’re just quantum probabilistic: Researchers explain human decision-making with physics theory
http://phys.org/news/2015-09-youre-irrational-quantum-probabilistic-human.html
It’s life, but not as we know it: Chatty cells found to be using ‘quantum communication’, which could reverse the ageing process
http://www.scmp.com/tech/science-research/article/1878562/its-life-not-we-know-it-chatty-cells-found-be-using-quantum
Transmission of DNA Genetic Information into Water by means of Electromagnetic Fields of Extremely-low Frequencies
http://vixra.org/abs/1202.0073
DNA waves and water
http://arxiv.org/PS_cache/arxiv/pdf/1012/1012.5166v1.pdf
Life is the bridge between Classical and Quantum Physics. Will be interesting to see if this conjecture is correct.